Our second Bruin Lab publication is out today in Scientific Reports. Here we show that a single high dose of a persistent pollutant (called dioxin or TCDD) leads to long-term metabolic dysregulation and impaired insulin secretion in mice. Importantly, female mice appear to be particularly susceptible to developing high blood sugar levels after dioxin exposure.
We are pleased to announce that the first Bruin Lab manuscript has been accepted for publication in Diabetologia. We show that cytochrome P450 enzymes (Cyp1a1) are induced and functional in mouse and human pancreatic islets following both in vitro and in vivo exposure.
What an awesome day. Our first MSc student (Erin MacFarlane) and SIX BSc students from the Bruin Lab graduated from Carleton today! We missed one student in the picture but managed to get everyone else in the same place at the same time.
Research Day 2019 was another success. The Bruin Lab had three outstanding Honour's Thesis students this year: Laura Harkness (L), Rayanna Merhi (M), and Kelsea McKay (R). As has become a tradition, we celebrated all the Honour's students after with the McKay Lab.
Today was a big day for the Bruin Lab. Myriam Hoyeck successfully completed her qualifying exam and is now our FIRST PhD student! We are so happy that she'll be staying on to continue studying the long-term consequences of development TCDD exposure in mice.